Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE

Circulating cell-free DNA (cfDNA) in the bloodstream originates from dying cells and is a promising noninvasive biomarker for cell death. Here, we propose an algorithm, CelFiE, to accurately estimate the relative abundances of cell types and tissues contributing to cfDNA from epigenetic cfDNA sequen...

Descripción completa

Detalles Bibliográficos
Autores principales: Caggiano, Christa, Celona, Barbara, Garton, Fleur, Mefford, Joel, Black, Brian L., Henderson, Robert, Lomen-Hoerth, Catherine, Dahl, Andrew, Zaitlen, Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113516/
https://www.ncbi.nlm.nih.gov/pubmed/33976150
http://dx.doi.org/10.1038/s41467-021-22901-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113516/
https://www.ncbi.nlm.nih.gov/pubmed/33976150
http://dx.doi.org/10.1038/s41467-021-22901-x

Ejemplares similares