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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients

B cell responses to tumor antigens occur early in breast tumors and may identify immunogenic drivers of tumorigenesis. Sixty-two candidate antigens were identified prior to palpable tumor development in TgMMTV-neu and C3(1)Tag transgenic mouse mammary tumor models. Five antigens (VPS35, ARPC2, SERBP...

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Detalles Bibliográficos
Autores principales: Stanton, Sasha E., Gad, Ekram, Ramos, Erik, Corulli, Lauren, Annis, James, Childs, Jennifer, Katayama, Hiroyuki, Hanash, Samir, Marks, Jeffrey, Disis, Mary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113561/
https://www.ncbi.nlm.nih.gov/pubmed/33976232
http://dx.doi.org/10.1038/s41523-021-00257-1