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A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes

COVID-19 pandemic caused by SARS-CoV-2 constitutes a global public health crisis with enormous economic consequences. Monoclonal antibodies against SARS-CoV-2 can provide an important treatment option to fight COVID-19, especially for the most vulnerable populations. In this work, potent antibodies...

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Detalles Bibliográficos
Autores principales: Guo, Yu, Huang, Lisu, Zhang, Guangshun, Yao, Yanfeng, Zhou, He, Shen, Shu, Shen, Bingqing, Li, Bo, Li, Xin, Zhang, Qian, Chen, Mingjie, Chen, Da, Wu, Jia, Fu, Dan, Zeng, Xinxin, Feng, Mingfang, Pi, Chunjiang, Wang, Yuan, Zhou, Xingdong, Lu, Minmin, Li, Yarong, Fang, Yaohui, Lu, Yun-Yueh, Hu, Xue, Wang, Shanshan, Zhang, Wanju, Gao, Ge, Adrian, Francisco, Wang, Qisheng, Yu, Feng, Peng, Yun, Gabibov, Alexander G., Min, Juan, Wang, Yuhui, Huang, Heyu, Stepanov, Alexey, Zhang, Wei, Cai, Yan, Liu, Junwei, Yuan, Zhiming, Zhang, Chen, Lou, Zhiyong, Deng, Fei, Zhang, Hongkai, Shan, Chao, Schweizer, Liang, Sun, Kun, Rao, Zihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113581/
https://www.ncbi.nlm.nih.gov/pubmed/33976198
http://dx.doi.org/10.1038/s41467-021-22926-2