Phase separation of EML4–ALK in firing downstream signaling and promoting lung tumorigenesis

EML4–ALK fusion, observed in about 3%–7% of human lung adenocarcinoma, is one of the most important oncogenic drivers in initiating lung tumorigenesis. However, it still remains largely unknown about how EML4–ALK fusion exactly fires downstream signaling and drives lung cancer formation. We here fin...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Zhen, Sun, Honghua, Yue, Meiting, Pan, Xinwen, Chen, Liang, Feng, Xinhua, Yan, Xiumin, Zhu, Xueliang, Ji, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113584/
https://www.ncbi.nlm.nih.gov/pubmed/33976114
http://dx.doi.org/10.1038/s41421-021-00270-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113584/
https://www.ncbi.nlm.nih.gov/pubmed/33976114
http://dx.doi.org/10.1038/s41421-021-00270-5

Ejemplares similares