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Donor and Recipient Age-Mismatches: The Potential of Transferring Senescence
In transplantation, donor and recipients frequently differ in age. Senescent cells accumulate in donor organs with aging and have the potential to promote senescence in adjacent cells when transferred into recipient animals. Characteristically, senescent cells secrete a myriad of pro-inflammatory, s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113632/ https://www.ncbi.nlm.nih.gov/pubmed/33995411 http://dx.doi.org/10.3389/fimmu.2021.671479 |