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Donor and Recipient Age-Mismatches: The Potential of Transferring Senescence

In transplantation, donor and recipients frequently differ in age. Senescent cells accumulate in donor organs with aging and have the potential to promote senescence in adjacent cells when transferred into recipient animals. Characteristically, senescent cells secrete a myriad of pro-inflammatory, s...

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Detalles Bibliográficos
Autores principales: Iske, Jasper, Matsunaga, Tomohisa, Zhou, Hao, Tullius, Stefan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113632/
https://www.ncbi.nlm.nih.gov/pubmed/33995411
http://dx.doi.org/10.3389/fimmu.2021.671479