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Three-Dimensional Model of Sub-Plasmalemmal Ca(2+) Microdomains Evoked by the Interplay Between ORAI1 and InsP(3) Receptors
Ca(2+) signaling plays an essential role in T cell activation, which is a key step to start an adaptive immune response. During the transition from a quiescent to a fully activated state, Ca(2+) microdomains characterized by reduced spatial and temporal extents are observed in the junctions between...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113648/ https://www.ncbi.nlm.nih.gov/pubmed/33995380 http://dx.doi.org/10.3389/fimmu.2021.659790 |