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Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake

Parvalbumin (PV) is a cytosolic Ca(2+)-binding protein highly expressed in fast skeletal muscle, contributing to an increased relaxation rate. Moreover, PV is an “atrogene” downregulated in most muscle atrophy conditions. Here, we exploit mice lacking PV to explore the link between the two PV functi...

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Detalles Bibliográficos
Autores principales: Butera, Gaia, Vecellio Reane, Denis, Canato, Marta, Pietrangelo, Laura, Boncompagni, Simona, Protasi, Feliciano, Rizzuto, Rosario, Reggiani, Carlo, Raffaello, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113653/
https://www.ncbi.nlm.nih.gov/pubmed/33951435
http://dx.doi.org/10.1016/j.celrep.2021.109087