Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson’s Disease

Oxidative stress, neuroinflammation and apoptosis are some of the key etiological factors responsible for dopamin(DA)ergic degeneration during Parkinson’s disease (PD), yet the downstream molecular mechanisms underlying neurodegeneration are largely unknown. Recently, a genome-wide association study...

Descripción completa

Detalles Bibliográficos
Autores principales: Saminathan, Hariharan, Ghosh, Anamitra, Zhang, Danhui, Song, Chunjuan, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113680/
https://www.ncbi.nlm.nih.gov/pubmed/33995031
http://dx.doi.org/10.3389/fphar.2021.631375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113680/
https://www.ncbi.nlm.nih.gov/pubmed/33995031
http://dx.doi.org/10.3389/fphar.2021.631375

Ejemplares similares