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Detection of genomic mutations in katG and rpoB genes among multidrug-resistant Mycobacterium tuberculosis isolates from Tehran, Iran

Multidrug-resistant (MDR) Mycobacterium tuberculosis strains, defined as resistant to at least isoniazid and rifampin, have emerged as a major worldwide health threat. Spontaneous point mutations in various genes of M. tuberculosis cause resistance to isoniazid, with the most frequent gene target be...

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Detalles Bibliográficos
Autores principales: Motavaf, B., Keshavarz, N., Ghorbanian, F., Firuzabadi, S., Hosseini, F., Zaker Bostanabad, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113720/
https://www.ncbi.nlm.nih.gov/pubmed/34012550
http://dx.doi.org/10.1016/j.nmni.2021.100879