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The lysosomal protein ABCD4 can transport vitamin B(12) across liposomal membranes in vitro

Vitamin B(12) (cobalamin) is an essential micronutrient for human health, and mutation and dysregulation of cobalamin metabolism are associated with serious diseases, such as methylmalonic aciduria and homocystinuria. Mutations in ABCD4 or LMBRD1, which encode the ABC transporter ABCD4 and lysosomal...

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Detalles Bibliográficos
Autores principales: Kitai, Katsuki, Kawaguchi, Kosuke, Tomohiro, Takenori, Morita, Masashi, So, Takanori, Imanaka, Tsuneo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113721/
https://www.ncbi.nlm.nih.gov/pubmed/33845046
http://dx.doi.org/10.1016/j.jbc.2021.100654