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The lysosomal protein ABCD4 can transport vitamin B(12) across liposomal membranes in vitro
Vitamin B(12) (cobalamin) is an essential micronutrient for human health, and mutation and dysregulation of cobalamin metabolism are associated with serious diseases, such as methylmalonic aciduria and homocystinuria. Mutations in ABCD4 or LMBRD1, which encode the ABC transporter ABCD4 and lysosomal...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113721/ https://www.ncbi.nlm.nih.gov/pubmed/33845046 http://dx.doi.org/10.1016/j.jbc.2021.100654 |