REL-1017 (Esmethadone) Increases Circulating BDNF Levels in Healthy Subjects of a Phase 1 Clinical Study

Brain-derived neurotrophic factor (BDNF), a neurotrophin widely expressed in the central nervous system, exhibits important effects on neural plasticity. BDNF has been implicated in the mechanism of action of ketamine, a N-methyl-d-aspartic acid receptor (NMDAR) antagonist with rapid anti-depressant...

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Detalles Bibliográficos
Autores principales: De Martin, Sara, Gabbia, Daniela, Folli, Franco, Bifari, Francesco, Fiorina, Paolo, Ferri, Nicola, Stahl, Stephen, Inturrisi, Charles E., Pappagallo, Marco, Traversa, Sergio, Manfredi, Paolo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113752/
https://www.ncbi.nlm.nih.gov/pubmed/33995104
http://dx.doi.org/10.3389/fphar.2021.671859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113752/
https://www.ncbi.nlm.nih.gov/pubmed/33995104
http://dx.doi.org/10.3389/fphar.2021.671859

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