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In vivo genome editing in single mammalian brain neurons through CRISPR-Cas9 and cytosine base editors
Gene manipulation is a useful approach for understanding functions of genes and is important for investigating basic mechanisms of brain function on the level of single neurons and circuits. Despite the development and the wide range of applications of CRISPR-Cas9 and base editors (BEs), their imple...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113754/ https://www.ncbi.nlm.nih.gov/pubmed/34025938 http://dx.doi.org/10.1016/j.csbj.2021.04.051 |