Altered T Follicular Helper Cell Subsets and Function in Chronic Lymphocytic Leukemia

Follicular helper T cells (T(FH)) have specialized properties in promoting normal B cell activation but their role in chronic lymphocytic leukemia (CLL) is unknown. We find that T(FH) cells are elevated in CLL patients and are phenotypically abnormal, expressing higher levels of PD-1, TIGIT, CD40L,...

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Detalles Bibliográficos
Autores principales: Wu, Xun, Fajardo-Despaigne, J. Ernesto, Zhang, Christine, Neppalli, Vishala, Banerji, Versha, Johnston, James B., Gibson, Spencer B., Marshall, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113764/
https://www.ncbi.nlm.nih.gov/pubmed/33996605
http://dx.doi.org/10.3389/fonc.2021.674492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113764/
https://www.ncbi.nlm.nih.gov/pubmed/33996605
http://dx.doi.org/10.3389/fonc.2021.674492

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