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Semisynthetic modifications of antitubercular lanostane triterpenoids from Ganoderma

Antitubercular lanostane triterpenoids isolated from mycelial cultures of the basidiomycete Ganoderma australe were structurally modified by semisynthesis. One of the synthetic compounds, named GA003 (9), showed more potent activity against Mycobacterium tuberculosis H37Ra than the lead natural lano...

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Detalles Bibliográficos
Autores principales: Chinthanom, Panida, Vichai, Vanicha, Dokladda, Kanchana, Sappan, Malipan, Thongpanchang, Chawanee, Isaka, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113785/
https://www.ncbi.nlm.nih.gov/pubmed/33981028
http://dx.doi.org/10.1038/s41429-021-00422-5