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Design, Synthesis and Pharmacological Evaluation of Naphthofuran Derivatives as Potent SIRT1 Activators

Diabetic nephropathy (DN) is one of the most important medical complications in diabetic patients, which is an essential cause of end-stage renal disease in diabetic patients and still lacks effective medicines. Silent information regulator 1 (SIRT1) is closely related to the occurrence and developm...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Chen, Qing-Qing, Huang, Ye, Li, Kai-Hang, Geng, Xiao-Ju, Wang, Tao, Lin, Qi-Si, Yao, Ruo-Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113817/
https://www.ncbi.nlm.nih.gov/pubmed/33995069
http://dx.doi.org/10.3389/fphar.2021.653233