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Design, Synthesis and Pharmacological Evaluation of Naphthofuran Derivatives as Potent SIRT1 Activators
Diabetic nephropathy (DN) is one of the most important medical complications in diabetic patients, which is an essential cause of end-stage renal disease in diabetic patients and still lacks effective medicines. Silent information regulator 1 (SIRT1) is closely related to the occurrence and developm...
Autores principales: | Gao, Jian, Chen, Qing-Qing, Huang, Ye, Li, Kai-Hang, Geng, Xiao-Ju, Wang, Tao, Lin, Qi-Si, Yao, Ruo-Si |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113817/ https://www.ncbi.nlm.nih.gov/pubmed/33995069 http://dx.doi.org/10.3389/fphar.2021.653233 |
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