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In silico Approaches for the Design and Optimization of Interfering Peptides Against Protein–Protein Interactions

Large contact surfaces of protein–protein interactions (PPIs) remain to be an ongoing issue in the discovery and design of small molecule modulators. Peptides are intrinsically capable of exploring larger surfaces, stable, and bioavailable, and therefore bear a high therapeutic value in the treatmen...

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Detalles Bibliográficos
Autores principales: Hashemi, Zahra Sadat, Zarei, Mahboubeh, Fath, Mohsen Karami, Ganji, Mahmoud, Farahani, Mahboube Shahrabi, Afsharnouri, Fatemeh, Pourzardosht, Navid, Khalesi, Bahman, Jahangiri, Abolfazl, Rahbar, Mohammad Reza, Khalili, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113820/
https://www.ncbi.nlm.nih.gov/pubmed/33996914
http://dx.doi.org/10.3389/fmolb.2021.669431