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In silico Approaches for the Design and Optimization of Interfering Peptides Against Protein–Protein Interactions
Large contact surfaces of protein–protein interactions (PPIs) remain to be an ongoing issue in the discovery and design of small molecule modulators. Peptides are intrinsically capable of exploring larger surfaces, stable, and bioavailable, and therefore bear a high therapeutic value in the treatmen...
Autores principales: | Hashemi, Zahra Sadat, Zarei, Mahboubeh, Fath, Mohsen Karami, Ganji, Mahmoud, Farahani, Mahboube Shahrabi, Afsharnouri, Fatemeh, Pourzardosht, Navid, Khalesi, Bahman, Jahangiri, Abolfazl, Rahbar, Mohammad Reza, Khalili, Saeed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113820/ https://www.ncbi.nlm.nih.gov/pubmed/33996914 http://dx.doi.org/10.3389/fmolb.2021.669431 |
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