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Targeting Neutrophil Adhesive Events to Address Vaso-Occlusive Crisis in Sickle Cell Patients

Neutrophils are essential to protect the host against invading pathogens but can promote disease progression in sickle cell disease (SCD) by becoming adherent to inflamed microvascular networks in peripheral tissue throughout the body. During the inflammatory response, leukocytes extravasate from th...

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Detalles Bibliográficos
Autores principales: Morikis, Vasilios A., Hernandez, Alfredo A., Magnani, John L., Sperandio, Markus, Simon, Scott I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113856/
https://www.ncbi.nlm.nih.gov/pubmed/33995392
http://dx.doi.org/10.3389/fimmu.2021.663886