Immunization With a DNA Vaccine Encoding the Toxoplasma gondii’ s GRA39 Prolongs Survival and Reduce Brain Cyst Formation in a Murine Model

Toxoplasma gondii, an obligate intracellular protozoan parasite, can cause infect almost all warm-blooded animals and humans. To evaluate the immunogenicity and protective efficacy of T. gondii GRA39 (TgGRA39) in mice by using DNA immunization, we constructed a recombinant eukaryotic plasmid pVAX-Tg...

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Detalles Bibliográficos
Autores principales: Zhu, Yuchao, Xu, Yanan, Hong, Lu, Zhou, Chunxue, Chen, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113873/
https://www.ncbi.nlm.nih.gov/pubmed/33995293
http://dx.doi.org/10.3389/fmicb.2021.630682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113873/
https://www.ncbi.nlm.nih.gov/pubmed/33995293
http://dx.doi.org/10.3389/fmicb.2021.630682

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