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CRISPR screen to determine the in vivo fitness of Toxoplasma genes

The virulence of eukaryotic parasites like Toxoplasma gondii depends on their capacity to escape from the host immune response and disseminate throughout the host organism. However, Toxoplasma gene products essential for its in vivo pathogenesis remain uncharacterized. Here, we present the complete...

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Detalles Bibliográficos
Autores principales: Sangaré, Lamba Omar, Wang, Yifan, Arranz-Solís, David, Saeij, Jeroen P.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113973/
https://www.ncbi.nlm.nih.gov/pubmed/34013213
http://dx.doi.org/10.1016/j.xpro.2021.100520