Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates

PURPOSE: The purpose of this study was to evaluate whether clinical grade recombinant adeno-associated virus serotype 8 (rAAV8) leads to increased appearance of hyper-reflective foci (HRF) in the retina of non-human primates (NHPs) following subretinal gene therapy injection. METHODS: Different dose...

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Detalles Bibliográficos
Autores principales: Rodríguez-Bocanegra, Eduardo, Wozar, Fabian, Seitz, Immanuel P., Reichel, Felix F. L., Ochakovski, Alex, Bucher, Kirsten, Wilhelm, Barbara, Bartz-Schmidt, K. Ulrich, Peters, Tobias, Fischer, M. Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114007/
https://www.ncbi.nlm.nih.gov/pubmed/34111260
http://dx.doi.org/10.1167/tvst.10.6.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114007/
https://www.ncbi.nlm.nih.gov/pubmed/34111260
http://dx.doi.org/10.1167/tvst.10.6.15

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