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Biophysical Compatibility of a Heterotrimeric Tyrosinase-TYRP1-TYRP2 Metalloenzyme Complex

Tyrosinase (TYR) is a copper-containing monooxygenase central to the function of melanocytes. Alterations in its expression or activity contribute to variations in skin, hair and eye color, and underlie a variety of pathogenic pigmentary phenotypes, including several forms of oculocutaneous albinism...

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Detalles Bibliográficos
Autores principales: Lavinda, Olga, Manga, Prashiela, Orlow, Seth J., Cardozo, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114058/
https://www.ncbi.nlm.nih.gov/pubmed/33995009
http://dx.doi.org/10.3389/fphar.2021.602206