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MicroRNA-19b Downregulates NR3C1 and Enhances Oxaliplatin Chemoresistance in Colon Cancer via the PI3K/AKT/mTOR Pathway

BACKGROUND: Identifying the genes and signaling pathways related to chemoresistance might facilitate the development of novel therapeutic strategies for colon cancer. In this study, we aimed to investigate the biological functions and underlying mechanisms of action of miR-19b and NR3C1, as well as...

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Detalles Bibliográficos
Autores principales: Han, Zhongbo, Zhang, Chao, Wang, Qingfeng, Li, Liang, Wang, Meng, Li, Xi, Yang, Chunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114261/
https://www.ncbi.nlm.nih.gov/pubmed/34017210
http://dx.doi.org/10.1177/11795549211012666