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BRAF(non-V600E) more frequently co-occurs with IDH1/2 mutations in adult patients with gliomas than in patients harboring BRAF(V600E) but without a survival advantage
BACKGROUND: The effects of BRAF(non-V600E) and BRAF(V600E) on the outcomes and the molecular characteristics of adult glioma patients are unknown and need to be explored, although BRAF(V600E) has been extensively studied in pediatric glioma. METHODS: Co-occurring mutations and copy number alteration...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114535/ https://www.ncbi.nlm.nih.gov/pubmed/33980169 http://dx.doi.org/10.1186/s12883-021-02224-6 |