BRAF(non-V600E) more frequently co-occurs with IDH1/2 mutations in adult patients with gliomas than in patients harboring BRAF(V600E) but without a survival advantage

BACKGROUND: The effects of BRAF(non-V600E) and BRAF(V600E) on the outcomes and the molecular characteristics of adult glioma patients are unknown and need to be explored, although BRAF(V600E) has been extensively studied in pediatric glioma. METHODS: Co-occurring mutations and copy number alteration...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wang, Maode, Jiang, Haitao, Wang, Tuo, Da, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114535/
https://www.ncbi.nlm.nih.gov/pubmed/33980169
http://dx.doi.org/10.1186/s12883-021-02224-6

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