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Remdesivir for the treatment of Covid-19: the value of biochemical studies
The nucleotide analogue prodrug remdesivir remains the only FDA-approved antiviral small molecule for the treatment of infection with SARS-CoV-2. Biochemical studies revealed that the active form of the drug targets the viral RNA-dependent RNA polymerase and causes delayed chain-termination. Delayed...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier B.V.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114811/ https://www.ncbi.nlm.nih.gov/pubmed/34052732 http://dx.doi.org/10.1016/j.coviro.2021.04.014 |