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In Vitro and In Situ Activity-Based Labeling of Fibroblast Activation Protein with UAMC1110-Derived Probes

Fibroblast activation protein (FAP) is a proline-selective protease that belongs to the S9 family of serine proteases. It is typically highly expressed in the tumor microenvironment (TME) and especially in cancer-associated fibroblasts, the main cell components of the tumor stroma. The exact role of...

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Detalles Bibliográficos
Autores principales: Van Rymenant, Yentl, Tanc, Muhammet, Van Elzen, Roos, Bracke, An, De Wever, Olivier, Augustyns, Koen, Lambeir, Anne-Marie, Kockx, Mark, De Meester, Ingrid, Van Der Veken, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114891/
https://www.ncbi.nlm.nih.gov/pubmed/33996747
http://dx.doi.org/10.3389/fchem.2021.640566