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Early Developmental EEG and Seizure Phenotypes in a Full Gene Deletion of Ubiquitin Protein Ligase E3A Rat Model of Angelman Syndrome

Angelman syndrome (AS) is a neurodevelopmental disorder with unique behavioral phenotypes, seizures, and distinctive electroencephalographic (EEG) patterns. Recent studies identified motor, social communication, and learning and memory deficits in a CRISPR engineered rat model with a complete matern...

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Detalles Bibliográficos
Autores principales: Born, Heather A., Martinez, Luis A., Levine, Amber T., Harris, Sarah E., Mehra, Shubhangi, Lee, Wai Ling, Dindot, Scott V., Nash, Kevin R., Silverman, Jill L., Segal, David J., Weeber, Edwin J., Anderson, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114899/
https://www.ncbi.nlm.nih.gov/pubmed/33531368
http://dx.doi.org/10.1523/ENEURO.0345-20.2020