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Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

BACKGROUND: Herbal remedies of Echinacea purpurea tinctures are widely used today to reduce common cold respiratory tract infections. METHODS: Transcriptome, epigenome and kinome profiling allowed a systems biology level characterisation of genomewide immunomodulatory effects of a standardized Echin...

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Detalles Bibliográficos
Autores principales: Declerck, Ken, Novo, Claudina Perez, Grielens, Lisa, Van Camp, Guy, Suter, Andreas, Vanden Berghe, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8114977/
https://www.ncbi.nlm.nih.gov/pubmed/33980308
http://dx.doi.org/10.1186/s12906-021-03310-5