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C646 inhibits G2/M cell cycle-related proteins and potentiates anti-tumor effects in pancreatic cancer

The activity of histone acetyltransferases (HATs) plays a central role in an epigenetic modification in cooperation with HDACs (histone deacetyl transferases). It is likely that malfunction of this enzymatic machinery controlling epigenetic modification is relevant to carcinogenesis and tumor progre...

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Detalles Bibliográficos
Autores principales: Ono, Hiroaki, Kato, Tomotaka, Murase, Yoshiki, Nakamura, Yutaro, Ishikawa, Yoshiya, Watanabe, Shuichi, Akahoshi, Keiichi, Ogura, Toshiro, Ogawa, Kosuke, Ban, Daisuke, Kudo, Atsushi, Akiyama, Yoshimitsu, Tanaka, Shinji, Ito, Hiromichi, Tanabe, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115044/
https://www.ncbi.nlm.nih.gov/pubmed/33980911
http://dx.doi.org/10.1038/s41598-021-89530-8