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Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions

A unique enantioselective nickel-catalyzed vinylation of 2-azaallyl anions is advanced for the first time. This method affords diverse vinyl aryl methyl amines with high enantioselectivities, which are frequently occurring scaffolds in natural products and medications. This C–H functionalization met...

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Detalles Bibliográficos
Autores principales: Duan, Shengzu, Deng, Guogang, Zi, Yujin, Wu, Xiaomei, Tian, Xun, Liu, Zhengfen, Li, Minyan, Zhang, Hongbin, Yang, Xiaodong, Walsh, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115067/
https://www.ncbi.nlm.nih.gov/pubmed/34084440
http://dx.doi.org/10.1039/d1sc00972a