Correlation between the structure and skin permeability of compounds

A three-descriptor quantitative structure–activity/toxicity relationship (QSAR/QSTR) model was developed for the skin permeability of a sufficiently large data set consisting of 274 compounds, by applying support vector machine (SVM) together with genetic algorithm. The optimal SVM model possesses t...

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Detalles Bibliográficos
Autores principales: Zeng, Ruolan, Deng, Jiyong, Dang, Limin, Yu, Xinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115152/
https://www.ncbi.nlm.nih.gov/pubmed/33980965
http://dx.doi.org/10.1038/s41598-021-89587-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115152/
https://www.ncbi.nlm.nih.gov/pubmed/33980965
http://dx.doi.org/10.1038/s41598-021-89587-5

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