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Differential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function

Lithium salts are used as mood-balancing medication prescribed to patients suffering from neuropsychiatric disorders, such as bipolar disorder and major depressive disorder. Lithium salts cross the blood-brain barrier and reach the brain parenchyma within few hours after oral application, however, h...

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Detalles Bibliográficos
Autores principales: Izsak, Julia, Seth, Henrik, Iljin, Margarita, Theiss, Stephan, Ågren, Hans, Funa, Keiko, Aigner, Ludwig, Hanse, Eric, Illes, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115174/
https://www.ncbi.nlm.nih.gov/pubmed/33980815
http://dx.doi.org/10.1038/s41398-021-01399-3