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Fas/FasL mediates NF-κBp65/PUMA-modulated hepatocytes apoptosis via autophagy to drive liver fibrosis

Fas/Fas ligand (FasL)-mediated cell apoptosis involves a variety of physiological and pathological processes including chronic hepatic diseases, and hepatocytes apoptosis contributes to the development of liver fibrosis following various causes. However, the mechanism of the Fas/FasL signaling and h...

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Detalles Bibliográficos
Autores principales: Tan, Siwei, Liu, Xianzhi, Chen, Lingjun, Wu, Xiaoqin, Tao, Li, Pan, Xuemei, Tan, Shuyan, Liu, Huiling, Jiang, Jie, Wu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115181/
https://www.ncbi.nlm.nih.gov/pubmed/33980818
http://dx.doi.org/10.1038/s41419-021-03749-x