Atorvastatin Upregulates microRNA-186 and Inhibits the TLR4-Mediated MAPKs/NF-κB Pathway to Relieve Steroid-Induced Avascular Necrosis of the Femoral Head

Steroid-induced avascular necrosis of the femoral head (SANFH) is caused by the death of active components of the femoral head owing to hormone overdoses. The use of lipid-lowering drugs to prevent SANFH in animals inspired us to identify the mechanisms involving Atorvastatin (Ato) in SANFH. However...

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Detalles Bibliográficos
Autores principales: Zhang, Yusong, Ma, Limin, Lu, Erhai, Huang, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115218/
https://www.ncbi.nlm.nih.gov/pubmed/33995003
http://dx.doi.org/10.3389/fphar.2021.583975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115218/
https://www.ncbi.nlm.nih.gov/pubmed/33995003
http://dx.doi.org/10.3389/fphar.2021.583975

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