The anesthetic sevoflurane induces tau trafficking from neurons to microglia

Accumulation and spread of tau in Alzheimer’s disease and other tauopathies occur in a prion-like manner. However, the mechanisms and downstream consequences of tau trafficking remain largely unknown. We hypothesized that tau traffics from neurons to microglia via extracellular vesicles (EVs), leadi...

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Detalles Bibliográficos
Autores principales: Dong, Yuanlin, Liang, Feng, Huang, Lining, Fang, Fang, Yang, Guang, Tanzi, Rudolph E., Zhang, Yiying, Quan, Qimin, Xie, Zhongcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115254/
https://www.ncbi.nlm.nih.gov/pubmed/33980987
http://dx.doi.org/10.1038/s42003-021-02047-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115254/
https://www.ncbi.nlm.nih.gov/pubmed/33980987
http://dx.doi.org/10.1038/s42003-021-02047-8

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