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Research on the Species Difference of the Hepatotoxicity of Medicine Based on Transcriptome

In recent years, several drugs have been withdrawn from use by regulatory bodies owing to hepatotoxicity; therefore, studies on drug-induced liver injury (DILI) are being actively pursued. Most studies evaluating DILI use rats or mice as animal models to determine drug toxicity; however, the toxicit...

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Detalles Bibliográficos
Autores principales: Xu, Ziying, Kang, Qianjun, Yu, Zihui, Tian, Lichun, Zhang, Jingxuan, Wang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115263/
https://www.ncbi.nlm.nih.gov/pubmed/33995060
http://dx.doi.org/10.3389/fphar.2021.647084