Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signaling

Endothelial barrier integrity is ensured by the stability of the adherens junction (AJ) complexes comprised of vascular endothelial (VE)-cadherin as well as accessory proteins such as β-catenin and p120-catenin. Disruption of the endothelial barrier due to disassembly of AJs results in tissue edema...

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Detalles Bibliográficos
Autores principales: Kim, Young-Mee, Krantz, Sarah, Jambusaria, Ankit, Toth, Peter T., Moon, Hyung-Geun, Gunarathna, Isuru, Park, Gye Young, Rehman, Jalees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115264/
https://www.ncbi.nlm.nih.gov/pubmed/33980844
http://dx.doi.org/10.1038/s41467-021-23047-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115264/
https://www.ncbi.nlm.nih.gov/pubmed/33980844
http://dx.doi.org/10.1038/s41467-021-23047-6

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