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Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer’s disease mouse model

Conjugated linoleic acid (CLA) is an isomer of linoleic acid (LA). The predominant dietary CLA is cis-9, trans-11-CLA (c-9, t-11-CLA), which constitutes up to ~ 90% of total CLA and is thought to be responsible for the positive health benefits associated with CLA. However, the effects of c-9, t-11-C...

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Detalles Bibliográficos
Autores principales: Fujita, Yu, Kano, Kuniyuki, Kishino, Shigenobu, Nagao, Toshihiro, Shen, Xuefeng, Sato, Chiharu, Hatakeyama, Hatsune, Ota, Yume, Niibori, Sho, Nomura, Ayako, Kikuchi, Kota, Yasuno, Wataru, Takatori, Sho, Kikuchi, Kazunori, Sano, Yoshitake, Tomita, Taisuke, Suzuki, Toshiharu, Aoki, Junken, Zou, Kun, Natori, Shunji, Komano, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115273/
https://www.ncbi.nlm.nih.gov/pubmed/33980877
http://dx.doi.org/10.1038/s41598-021-88870-9