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Ultraviolet light-induced collagen degradation inhibits melanoma invasion

Ultraviolet radiation (UVR) damages the dermis and fibroblasts; and increases melanoma incidence. Fibroblasts and their matrix contribute to cancer, so we studied how UVR modifies dermal fibroblast function, the extracellular matrix (ECM) and melanoma invasion. We confirmed UVR-damaged fibroblasts p...

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Detalles Bibliográficos
Autores principales: Budden, Timothy, Gaudy-Marqueste, Caroline, Porter, Andrew, Kay, Emily, Gurung, Shilpa, Earnshaw, Charles H., Roeck, Katharina, Craig, Sarah, Traves, Víctor, Krutmann, Jean, Muller, Patricia, Motta, Luisa, Zanivan, Sara, Malliri, Angeliki, Furney, Simon J., Nagore, Eduardo, Virós, Amaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115293/
https://www.ncbi.nlm.nih.gov/pubmed/33980846
http://dx.doi.org/10.1038/s41467-021-22953-z