CellectSeq: In silico discovery of antibodies targeting integral membrane proteins combining in situ selections and next-generation sequencing

Synthetic antibody (Ab) technologies are efficient and cost-effective platforms for the generation of monoclonal Abs against human antigens. Yet, they typically depend on purified proteins, which exclude integral membrane proteins that require the lipid bilayers to support their native structure and...

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Detalles Bibliográficos
Autores principales: Kelil, Abdellali, Gallo, Eugenio, Banerjee, Sunandan, Adams, Jarrett J., Sidhu, Sachdev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115320/
https://www.ncbi.nlm.nih.gov/pubmed/33980972
http://dx.doi.org/10.1038/s42003-021-02066-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115320/
https://www.ncbi.nlm.nih.gov/pubmed/33980972
http://dx.doi.org/10.1038/s42003-021-02066-5

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