Cargando…

CellectSeq: In silico discovery of antibodies targeting integral membrane proteins combining in situ selections and next-generation sequencing

Synthetic antibody (Ab) technologies are efficient and cost-effective platforms for the generation of monoclonal Abs against human antigens. Yet, they typically depend on purified proteins, which exclude integral membrane proteins that require the lipid bilayers to support their native structure and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kelil, Abdellali, Gallo, Eugenio, Banerjee, Sunandan, Adams, Jarrett J., Sidhu, Sachdev S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115320/ https://www.ncbi.nlm.nih.gov/pubmed/33980972 http://dx.doi.org/10.1038/s42003-021-02066-5

Ejemplares similares

In situ antibody phage display yields optimal inhibitors of integrin α11/β1
por: Gallo, Eugenio, et al.
Publicado: (2020)

CellECT: cell evolution capturing tool
por: Delibaltov, Diana L., et al.
Publicado: (2016)

Fast and Accurate Discovery of Degenerate Linear Motifs in Protein Sequences
por: Kelil, Abdellali, et al.
Publicado: (2014)

A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models
por: Ling, Binbing, et al.
Publicado: (2017)

CLUSS: Clustering of protein sequences based on a new similarity measure
por: Kelil, Abdellali, et al.
Publicado: (2007)

Exhaustive search of linear information encoding protein-peptide recognition
por: Kelil, Abdellali, et al.
Publicado: (2017)

Rapid On-Cell Selection of High-Performance Human Antibodies
por: Philpott, David N., et al.
Publicado: (2021)

USP10 Promotes Fibronectin Recycling, Secretion, and Organization
por: Phillips, Andrew T., et al.
Publicado: (2021)

Large‐scale survey and database of high affinity ligands for peptide recognition modules
por: Teyra, Joan, et al.
Publicado: (2020)

Biosynthetic Oligoclonal Antivenom (BOA) for Snakebite and Next-Generation Treatments for Snakebite Victims †
por: Kini, R. Manjunatha, et al.
Publicado: (2018)

In Silico: Where Next?
por: Fairhall, Adrienne L.
Publicado: (2021)

HISS: Snakemake-based workflows for performing SMRT-RenSeq assembly, AgRenSeq and dRenSeq for the discovery of novel plant disease resistance genes
por: Adams, Thomas M., et al.
Publicado: (2023)

In Silico Pooling of ChIP-seq Control Experiments
por: Sun, Guannan, et al.
Publicado: (2014)

Simulating Illumina metagenomic data with InSilicoSeq
por: Gourlé, Hadrien, et al.
Publicado: (2019)

Promises and caveats of in silico biomarker discovery
por: Pusztai, L, et al.
Publicado: (2008)

In Silico Strategies in Tuberculosis Drug Discovery
por: Macalino, Stephani Joy Y., et al.
Publicado: (2020)

Next-Generation Molecular Discovery: From Bottom-Up In Vivo and In Vitro Approaches to In Silico Top-Down Approaches for Therapeutics Neogenesis
por: Kenny, Sophie E., et al.
Publicado: (2022)

Is RAD-seq suitable for phylogenetic inference? An in silico assessment and optimization
por: Cariou, Marie, et al.
Publicado: (2013)

In silico discovery of human natural antisense transcripts
por: Li, Yuan-Yuan, et al.
Publicado: (2006)

In silico discovery of terpenoid metabolism in Cannabis sativa
por: Massimino, Luca
Publicado: (2017)

Editorial: In silico Methods for Drug Design and Discovery
por: Brogi, Simone, et al.
Publicado: (2020)

In silico discovery of blood cell macromolecular associations
por: Gautvik, Kaare M., et al.
Publicado: (2022)

In Silico Discovery of Anticancer Peptides from Sanghuang
por: Liu, Minghao, et al.
Publicado: (2022)

A T cell redirection platform for co-targeting dual antigens on solid tumors
por: Enderle, Leonie, et al.
Publicado: (2021)

SeqFeatR for the Discovery of Feature-Sequence Associations
por: Budeus, Bettina, et al.
Publicado: (2016)

Discovery of Protein–lncRNA Interactions by Integrating Large-Scale CLIP-Seq and RNA-Seq Datasets
por: Li, Jun-Hao, et al.
Publicado: (2015)

NextGen microbial natural products discovery
por: Schmidt-Dannert, Claudia
Publicado: (2015)

Next Generation Sequencing for Detection and Discovery of Plant Viruses and Viroids: Comparison of Two Approaches
por: Pecman, Anja, et al.
Publicado: (2017)

In silico discovery of transcription regulatory elements in Plasmodium falciparum
por: Young, Jason A, et al.
Publicado: (2008)

In silico pharmacology for drug discovery: applications to targets and beyond
por: Ekins, S, et al.
Publicado: (2007)

In Silico Discovery of Aminoacyl-tRNA Synthetase Inhibitors
por: Zhao, Yaxue, et al.
Publicado: (2014)

In silico pharmacology: drug design and discovery’s gate to the future
por: Noori, Hamid R, et al.
Publicado: (2013)

In silico drug combination discovery for personalized cancer therapy
por: Jeon, Minji, et al.
Publicado: (2018)

In Silico Discovery of Candidate Drugs against Covid-19
por: Cava, Claudia, et al.
Publicado: (2020)

In Silico discovery of aptamers with an enhanced library design strategy
por: Chen, Long, et al.
Publicado: (2023)

Effect of “magic chlorine” in drug discovery: an in silico approach
por: Joshi, Sravani, et al.
Publicado: (2023)

Discovery of Replicating Circular RNAs by RNA-Seq and Computational Algorithms
por: Zhang, Zhixiang, et al.
Publicado: (2014)

TagSeq: Malicious behavior discovery using dynamic analysis
por: Huang, Yi-Ting, et al.
Publicado: (2022)

Next-generation vaccines and the impacts of state-of-the-art in-silico technologies
por: Salemi, Aysan, et al.
Publicado: (2021)

BEERS2: RNA-Seq simulation through high fidelity in silico modeling
por: Brooks, Thomas G., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v1c6pf39hg5ska28g45ncue44d