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Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses

The risks of non-alcoholic fatty liver disease (NAFLD) include obese and non-obese stresses such as chronic hepatitis C virus (HCV) infection, but the regulatory determinants remain obscure. Apolipoprotein J (ApoJ) served as an ER-Golgi contact-site chaperone near lipid droplet (LD), facilitating HC...

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Detalles Bibliográficos
Autores principales: Sun, Hung-Yu, Chen, Tzu-Ying, Tan, Yu-Ching, Wang, Chun-Hsiang, Young, Kung-Chia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115332/
https://www.ncbi.nlm.nih.gov/pubmed/33980978
http://dx.doi.org/10.1038/s42003-021-02093-2