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Simultaneous onset of type 1 diabetes mellitus and silent thyroiditis under durvalumab treatment

Durvalumab, a human immunoglobulin G1 kappa monoclonal antibody that blocks the interaction of programmed cell death ligand 1 (PD-L1) with the PD-1 and CD80 (B7.1) molecules, is increasingly used in advanced neoplasias. Durvalumab use is associated with increased immune-related adverse events. We re...

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Detalles Bibliográficos
Autores principales: León Mengíbar, Jose, Capel, Ismael, Bonfill, Teresa, Mazarico, Isabel, Casamitjana Espuña, Laia, Caixàs, Assumpta, Rigla, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115434/
https://www.ncbi.nlm.nih.gov/pubmed/31310083
http://dx.doi.org/10.1530/EDM-19-0045