Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells

Misfolding of the cellular prion protein, PrP(C), into the amyloidogenic isoform, PrP(Sc), which forms infectious protein aggregates, the so-called prions, is a key pathogenic event in prion diseases. No pathogens other than prions have been identified to induce misfolding of PrP(C) into PrP(Sc) and...

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Detalles Bibliográficos
Autores principales: Hara, Hideyuki, Chida, Junji, Uchiyama, Keiji, Pasiana, Agriani Dini, Takahashi, Etsuhisa, Kido, Hiroshi, Sakaguchi, Suehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115602/
https://www.ncbi.nlm.nih.gov/pubmed/33980968
http://dx.doi.org/10.1038/s41598-021-89586-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115602/
https://www.ncbi.nlm.nih.gov/pubmed/33980968
http://dx.doi.org/10.1038/s41598-021-89586-6

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