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The nucleoplasmic interactions among Lamin A/C-pRB-LAP2α-E2F1 are modulated by dexamethasone

Ataxia telangiectasia (AT) is a rare genetic neurodegenerative disease. To date, there is no available cure for the illness, but the use of glucocorticoids has been shown to alleviate the neurological symptoms associated with AT. While studying the effects of dexamethasone (dex) in AT fibroblasts, b...

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Detalles Bibliográficos
Autores principales: Ricci, Anastasia, Orazi, Sara, Biancucci, Federica, Magnani, Mauro, Menotta, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115688/
https://www.ncbi.nlm.nih.gov/pubmed/33980953
http://dx.doi.org/10.1038/s41598-021-89608-3