Genome-wide proximity between RNA polymerase and DNA topoisomerase I supports transcription in Streptococcus pneumoniae

Streptococcus pneumoniae is a major cause of disease and death that develops resistance to multiple antibiotics. DNA topoisomerase I (TopoI) is a novel pneumococcal drug target. TopoI is the sole type-I pneumococcal topoisomerase that regulates supercoiling homeostasis in this bacterium. In this stu...

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Detalles Bibliográficos
Autores principales: Ferrándiz, María-José, Hernández, Pablo, de la Campa, Adela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115823/
https://www.ncbi.nlm.nih.gov/pubmed/33930020
http://dx.doi.org/10.1371/journal.pgen.1009542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115823/
https://www.ncbi.nlm.nih.gov/pubmed/33930020
http://dx.doi.org/10.1371/journal.pgen.1009542

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