Interplay between H1N1 influenza a virus infection, extracellular and intracellular respiratory tract pH, and host responses in a mouse model

During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different isolates vary in the pH at which they become activated in endosomes or become irreversible inactiv...

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Detalles Bibliográficos
Autores principales: Okda, Faten A., Perry, S. Scott, Webby, Richard J., Russell, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115840/
https://www.ncbi.nlm.nih.gov/pubmed/33979408
http://dx.doi.org/10.1371/journal.pone.0251473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115840/
https://www.ncbi.nlm.nih.gov/pubmed/33979408
http://dx.doi.org/10.1371/journal.pone.0251473

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