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Interplay between H1N1 influenza a virus infection, extracellular and intracellular respiratory tract pH, and host responses in a mouse model
During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different isolates vary in the pH at which they become activated in endosomes or become irreversible inactiv...
Autores principales: | Okda, Faten A., Perry, S. Scott, Webby, Richard J., Russell, Charles J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8115840/ https://www.ncbi.nlm.nih.gov/pubmed/33979408 http://dx.doi.org/10.1371/journal.pone.0251473 |
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